Established since 1921, Santasiero's Restaurant has remained a cornerstone of traditional Italian dining in Buffalo, New York. Its humble, 1920s-style digs provide a nostalgic ambiance for guests seeking casual Italian comfort food. Indulge in the family's signature pasta fagioli and delectable meatballs or other beloved Italian specialties as you relish the homey atmosphere at Santasiero's. Indoor dining requires reservations, ensuring a unique and intimate experience that has delighted visitors for generations.