Luisa's Restaurant Wine Bar Since 1959 is an authentic Italian restaurant located in San Francisco, CA. Our establishment has been operating since 1959 and is a perfect choice for the entire family, boasting a warm and welcoming atmosphere. We pride ourselves on providing friendly and attentive customer service, along with great prices, and, naturally, delicious Italian cuisine. As the best Italian food spot in San Francisco, CA, dining with us creates an experience reminiscent of Italy itself!