As one of the most innovative restaurants in San Diego, we are committed to changing the way our guests think about food. Everything we do is made from scratch and with love. From our signature breads to our fruit-infused sangrias, something is always cooking at Cafe 21 San Diego. Our concept is small plates, allowing for variety and guests to indulge in different tastes and flavors. With an eclectic and unique menu offering, Cafe 21 is the most flavorful and interesting California fusion kitchen in SoCal. What is important to you is important to us and we are here to meet your tastes, accommodating gluten-free, vegetarian, and vegan guests. Be ready to experience Nature’s Kitchen as interpreted by our revered and most inventive Chef Leyla.